Fitness
Glycogen Depletion Run
A glycogen depletion run is a long aerobic session that drains muscle glycogen for advanced endurance adaptations—requiring careful refeeding and recovery afterward.
A glycogen depletion run is a long or double-session aerobic workout that significantly lowers muscle glycogen—sometimes used in advanced endurance blocks to improve fat oxidation and storage supercompensation when followed by proper refeeding. It is not for weekly repetition; poor recovery raises illness and injury risk.
Refuel with adequate carbs and protein within hours.
Common questions
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Are fasted long runs the same as depletion runs?
Fasted runs stress fueling differently; true depletion often means very long duration or two-a-days. Both demand refeeding—do not stack them weekly without coaching context.
Related terms
Put Glycogen Depletion Run into practice
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