Nutrition
tTG-IgA Celiac Screening
tTG-IgA celiac screening is first-line blood work while eating gluten—with total IgA checked to catch false negatives from IgA deficiency.
tTG-IgA celiac screening measures antibodies against tissue transglutaminase while you consume gluten—first-line blood work before biopsy. Total IgA should be checked because IgA deficiency can yield false negatives; IgG-based tests back up those cases.
Antibody levels often fall on a gluten-free diet, so screening after going GF misleads.
Common questions
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How long must you eat gluten before tTG-IgA testing?
Clinicians often recommend weeks of daily gluten—sometimes two to six weeks or more—after prior GF eating. Follow your gastroenterologist's protocol; do not guess duration from forums.
Related terms
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