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Nutrition

Post-Ingestive Satiety Signal

Post-ingestive satiety signals come from nutrients in the gut and blood—protein and fiber sustain fullness longer than ultra-processed calorie hits.

Post-ingestive satiety signals arise after nutrients hit the gut and blood—peptide YY, GLP-1, cholecystokinin, and glucose stability—telling the brain to reduce appetite for hours. Protein, fiber, and balanced meals sustain these signals; ultra-processed hits can spike reward while failing to hold fullness.

Liquid calories often weaken post-ingestive feedback.

Common questions

  • Why am I hungry again after fast food?

    Hyper-palatable low-fiber meals can spike reward without durable post-ingestive hormone support. Adding protein, produce, and whole-food volume usually extends the gap to the next meal.

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