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Nutrition

Bile Acid Liver–Gut Axis

Bile acid liver–gut axis: liver-made bile digests fat and talks to gut microbes—extreme low-fat diets can disrupt the rhythm.

The bile acid liver–gut axis describes how the liver makes bile for fat digestion and how gut microbes recycle bile acids that influence inflammation and glucose. Very low-fat crash diets or rapid weight loss can upset rhythm and cause loose stools in some people.

Moderate healthy fats at meals support gallbladder emptying.

Common questions

  • Should NAFLD diets cut all dietary fat?

    No—quality fats in moderate amounts support bile flow and adherence; cut refined carbs and sugary drinks before eliminating olive oil, fish, and nuts.

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