Nutrition
Leptin Sensitivity
Leptin sensitivity is how well the brain hears leptin's satiety signal. Deficits, poor sleep, and visceral fat can blunt it, increasing hunger despite adequate calories.
Leptin sensitivity is how well the brain responds to leptin—the satiety hormone from fat cells—rather than how much leptin is produced. Chronic deficits, poor sleep, and excess visceral fat can blunt signaling so fullness feels delayed.
Refeeds, adequate sleep, and gradual fat-loss phases help restore sensitivity in many people.
Common questions
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Can refeeds improve leptin sensitivity?
Planned higher-carb refeeds at maintenance during long deficits can temporarily restore leptin signaling and training quality. They are structured, not binge weekends.
Related terms
Put Leptin Sensitivity into practice
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